RNA Details
Disease Name
nephrolithiasis
Tissue
kidney
RNA Symbol
CXCR4
RNA ID
7852
RNA Type
mRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
RNA sequencing;qRT-PCR;immunohistochemistry etc.
Target
NA
Pathway
NF-KAPPA B SIGNALING PATHWAY
PubMed ID
35255299
Title
CXCR4 inhibition attenuates calcium oxalate crystal deposition-induced renal fibrosis
Year
2022
Function
CXCR4 inhibition attenuates CaOx crystal deposition-induced renal fibrosis by suppressing autophagy and EMT through the NF-kB pathway.